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Lab Notes

Solution for Scars on Trial

We worked with Prof Bayat’s team at Manchester University to carry out a double blind clinical trial with Solution for Scars and a placebo.

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Prof Bayat in the Laboratory at Manchester University

We stand by the science behind all our products and in 2018 / 2019 we put Solution for Scars on trial at Manchester University and tested our cream on real life humans.

The Clinical Trial

In a double-blinded randomised clinical trial we tested the effects of applying Solution for Scars. Live human volunteers all had identical biopsies to remove a plug of skin from their upper arms, to create a fresh wound.

The participants were split into four groups, half who were treated with Solution for Scars cream and half with a placebo cream without the active ingredient.

Each group was further split into two with one cohort having their wounds zonally primed either with the Solution for Scars or the placebo, and the rest not treated for two weeks until after the scar was formed.

“We have now shown that with Solution for Scars we can not only improve the quality of the scar so they are less thick, less red, but that by applying the cream early we can modify the quality of the scar for a better end result.” Prof Bayat

Founder of Science of Skin & Skin Biologist

Key Results

We found Solution for Scars cream dramatically improves scarring, reducing the thickness of scars by 20% and redness by 40%, within four to six weeks

Clinically Proven

Improves the appearance of scarring

Reduces scar thickness by up to 20%

Reduces scar redness by up to 40%

Increases scar mobility

Increases scar hydration

The Trial Results

In a breakthrough discovery, our trial also revealed that Solution for Scars starts working immediately at a cellular level, when applied to the skin around a fresh wound before a scar has even begun to form.

The trial observed a dramatic 60% reduction in the number of ‘mast cells’ in patients who had the skin around their wounds ‘zonally primed’ with Solution for Scars in the first two weeks.

Ardeshir Bayat in his lab

Prof Bayat in the Laboratory at Manchester University

Trial Figure One Trial Figure Two Trial Figure Three Trial Figure Four

Mast cells are triggered as part of the body’s immune response to being wounded and cause the prolonged inflammation, which leads to redness, itchiness and scarring.

These ground-breaking results have been published in a peer-reviewed paper available on-line in the internationally respected Journal of Investigative Dermatology.

Download our full clinical trial here:

Download Trial

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